The symptoms of the plague vary according
to the different constitutions of
the persons whom it attacks, and the season
of the year in which it appears. Sometimes
it wears the mask of other diseases;
but in general it is ushered in by head-ach,
stupor, resembling intoxication, shiverings,
depression of spirits, and loss of strength;
these are followed by some degree of fever,
together with nausea and vomiting. The
eyes become red, the countenance melancholy,
and the tongue white and foul. In
this state of things, the patients are sometimes
capable of sitting up, and going about
for some hours, or even a day or two. They
feel an itching or pain in those parts of the body where buboes and carbuncles are about
to appear. During the height of the plague,
many of the infected die on the second or
third day, before these tumours have time to
come out, and with no other external marks
except petechiæ or purple spots, which appear
a short time before death; in some these
spots are altogether wanting. The buboes
and carbuncles generally come out on the
second or third day, seldom on the fourth.
In some instances, the plague appears under
the form of an inflammatory disorder,
being accompanied with great heat, thirst,
high-coloured urine, flushed cheeks, and violent
delirium or phrensy; but in the greater
number of cases it assumes the type of a nervous
fever, being accompanied with little
heat and thirst, and pale and turbid urine;
the patients think themselves only slightly
indisposed, until a sudden prostration of
strength, and the eruption of buboes, carbuncles,
petechiæ or vibices, announce to
themselves, as well as to those who are about
them, the danger they are in. In some few instances, the plague appears under the form
of an intermittent fever.—Almost all those
who are carried off by this disorder, die before
the sixth day; those who get over
the seventh day have a good chance of recovery[39].
The diversity of symptoms above-noticed,
has given rise to the opinion that there are
three different species of the plague, viz. one
which is accompanied with petechiæ, another
with carbuncles, and a third with buboes;
but the history which we have given,
clearly proves, that these are only shades or
modifications of one and the same disorder,
which is more or less violent under different
circumstances and at different seasons. Petechiæ,
buboes, and carbuncles often appear
at the same time in the same patient, or occur
in succession. In the month of July,
great numbers of the impested died before
the tumours came out, having petechiæ only;
whereas in August and September, almost
every patient had petechiæ, joined with buboes
and carbuncles. After the middle of
October, when the contagion was less virulent,
although it still produced petechiæ and
carbuncles, yet they were neither so malignant
nor so frequent. Before this period,
scarcely four patients in a hundred recovered;
whereas during the latter months of the year,
the proportion of recoveries was much
greater. Sydenham has made the same observation
respecting the plague at London[40].
Nature endeavours to throw off the poison by
buboes. Carbuncles and petechiæ are not critical eruptions; they only denote a putrid
condition of the humours, and a great degree
of acrimony; whence it follows, that
in proportion as buboes are more common,
and petechiæ and carbuncles more rare, the
milder the plague is[41].
To this account which Dr. Mertens has
given of the symptoms which the plague at
Moscow exhibited, we shall add the descriptions
drawn up by two other practitioners
(Orræus and Samoïlowitz,) who had great
opportunities of observation, and who have
been more particular in noticing some of the
phenomena than our author.
According to Orræus (Descriptio Pestis, &c.)
the plague in Russia appeared under
four different forms or varieties. Of these,
he terms the first, the period of infection; the second, the slow type; the third, the acute
type; and the fourth, the exceedingly acute
type.
1. In the period of infection (which is commonly
the forerunner of the other forms of
the plague) the contagion, less active and
virulent, keeps lurking in the body, and produces
the following symptoms, viz. sharp,
flying pains in the glandular parts (such as
the armpit and groins) and in the muscles of
the neck and breast; ardor urinæ; drowsiness;
an increased secretion of the sebaceous
humour, so that the skin is in many parts,
and more especially in the hands and face,
much more unctuous and glossy than usual;
the belly is costive, but when moved, there
comes away a great quantity of pulpy slimy
fæces; the patients complain of a heaviness
of the body (some compare their limbs to a
mass of lead), great lassitude and faintings.
A swelling, but without much pain, of
some gland (in the groin or armpit) together
with dark-red or brown spots, denote a higher degree of infection: and a bad taste
in the mouth, a viscidity of the saliva, loss
of appetite, whiteness and foulness of the
tongue, and head-ach, show that the patient
is going to be attacked with the plague under
one or other of the following types. The
above-mentioned symptoms, which continue
for a longer or shorter time (in some instances
for several days or even weeks) are not accompanied
with fever.
2. After the period of infection above described
has continued for some time without
yielding to medicine, it generally ends in the
slow type of the plague, which is characterized
by the following symptoms; viz. shiverings,
followed by a moderate degree of heat[42], a
febrile[43], unequal, for the most part weak,
and often intermitting pulse; a constant dull pain in the head (rather, according to the expression
of some patients, a heaviness, as if
the head was full of lead); urine pale and
turbid, but without sediment; tongue foul
and moist; very little thirst; depression of
spirits; belly costive during the first three or
four days, with inflation of the hypochondria
and borborygmi, but the abdomen
feels soft on pressure; there is frequent nausea
and vomiting of a slimy greenish-yellow
faburra[44]; petechiæ and other eruptions[45] make their appearance, in some sooner in others later; but in some they are altogether wanting.
The rudiments or germs of buboes
and carbuncles, which were forming during
the period of infection, now gradually increase
in size, but without being accompanied
with violent pain; and new ones arise
in other places; which, if they suppurate on
the fifth, sixth, or seventh day, save the life
of the patient: on the other hand, if no
suppuration takes place, and great debility,
diarrhœa, and delirium come on, the disease
terminates fatally, not, however, in some
cases till after the fourteenth day.
3. In the acute type, the plague is preceded
by a much shorter indisposition, sometimes
by none at all, suddenly seizing persons in
health. It is characterized by the following
symptoms: a bitter taste in the mouth, and
a viscidity of the saliva; violent head-ach[46]; redness of the eyes[47] and face; a very foul,
and sometimes dry tongue; chilliness succeeded
by considerable heat; a much fuller,
stronger, and quicker pulse than in the slow
type of the disorder, as well as more thirst,
and deeper coloured urine; costiveness; buboes,
and carbuncles come out soon after the
attack of fever, or at the same time with it;
after these, others come out; frequent vomitings
supervene, and a delirium, which is generally
of the low kind[48]. If, between the first and fourth day of the attack, the buboes are
resolved[49], or they, as well as the carbuncles,
come to suppuration, the patient recovers:
on the other hand, if no suppuration
takes place within that period; if the
buboes and carbuncles increase to a great size,
and the delirium continues, then the powers
of life become exhausted, the pulse sinks,
and death is ushered in by hæmorrhages, and
a copious exspuition of thin phlegm[50]. Death takes place on the third, fourth, or
fifth day; and it often happens, while the
corpse is yet warm, that petechiæ and other
spots come out. The bodies, after death,
appear remarkably pale, soft, somewhat tumid,
flexible, and free from fætor.
4. The plague, in its most acute type, attacks
in various ways; but in relation to the
leading symptoms, it may be reduced to two
forms: in the first, a person in perfect health,
without any previous marks of infection, is
suddenly seized with a short but violent shivering
fit, followed by a hot fit, which alternate
with each other several times; but
the external heat soon goes off, and the skin
feels cool. The pulse is hard and very
quick, with a most violent headach and intolerable
anxiety about the præcordia[51];
a furious delirium generally comes on; the
tongue is smooth, exceedingly dry, and after
a while becomes livid; the respiration is
short and laborious; the eyes, which are
more prominent than in the acute plague,
are very red and full of ferocity; the face and
neck are turgid, at first red and afterwards
livid; vomiting seldom comes on spontaneously.
Such as are seized with these violent
symptoms seldom live more that twenty-four
hours. Most of them die apoplectic, or in
a state of convulsive suffocation[52]; some,
however, expire in a more placid manner.
After death the bodies turn livid in those
parts where nature had endeavoured to throw
out buboes; and dark-coloured spots and vibices
appear in different places. In the other
mode of attack, the patients are affected with
debility from the beginning, which, together
with the anxietas præcordiorum, increases
every moment; so that unless timely
relief be given, death speedily comes on.
In these cases, the pulse is very quick, but
small, feeble, and at length imperceptible.
Sometimes there is a low delirium; but in
many instances the patients are sensible to
the last. These are all the febrile symptoms
that are observable. Rudiments or germs of
buboes are seen upon the dead bodies.
Of these two varieties of the plague in
its most acute form, the first was observed
to take place in persons of a robust constitution
and in full health, after making too
hearty a meal on food not easily digested, or
eating too much fruit, &c. The other variety
attacked those who were under the influence
of terror, or after immoderate venery,
bleeding, &c.
The very acute type of the plague is less
frequent than the other types, and often destroys
the patient before medical assistance is
called in; in so much that he who appeared
well yesterday, is to day carried to his grave.
In this species of the plague, I never saw
perfect carbuncles and exanthemata; but buboes
come out quickly after the attack, and
are seen considerably elevated and livid in the
dead bodies.
Such is the description of symptoms given
by Orræus, a diligent and accurate observer.
That published by Samoïlowitz[53], although it is not so circumstantial nor so
well digested, coincides in all essential points
with the above. This last author considers
the plague under three different aspects or
varieties, which correspond to the three periods
of its beginning, its height, and its decline.
In the first and last period, carbuncles and
confluent petechiæ, or broad maculæ, are very
rarely met with; whereas in the middle period,
when the disorder rages with the
greatest fury, they both occur in one and the
same subject, and denote the utmost danger.
At this period, (viz. when the plague is at
its height) the pestilential particles being
more virulent, more volatile, and more subtile,
enter the body more readily, act upon
it with greater force, and produce a disease
which runs its course with greater rapidity
than in either of the other two degrees or varieties
of the plague.
The symptoms in the first period of the
plague are few and moderate; they are for
the most part reducible to head-ache, vomiting,
and buboes; petechiæ rarely appear[54],
or if they do, they are distinct and very small;
carbuncles are hardly ever seen. This degree
of the plague terminates favourably by
a suppuration of the buboes, often without
any assistance from art. It may therefore be
termed the mild or benignant form of the
plague.
The next degree or variety is that which
occurs when the plague is at its height.
This is the most terrible form of the disorder.
All the symptoms are marked with violence.
The head-ache is incessant, and the vomiting
recurs frequently; the external characters
are numerous; carbuncles appear in various
parts of the body; the petechiæ or maculæ
are very large and confluent, and often turn
to carbuncles a short time before death.
This happens in the following manner: two, three, or four large petechiæ run together
and form a yellow pustule; sometimes a similar
pustule rises upon each petechia; in
either case, on opening the pustules, a true
carbuncle appears beneath. In some instances
the patient is seized from the first
with a furious delirium; at other times this
delirium or phrenitic state does not supervene
until the second, third, or fourth day. If
this disorder of the brain continues until the
seventh day, there are hopes of recovery; on
the other hand, if the delirium ceases on or
after the first or second day, and the patient
becomes tranquil and feeble, such an alteration
is a certain presage of death. If this
change took place in the morning, the patients
died in the evening; if in the evening, they
did not live over the night. At other times
torpor came on, and continued through the
whole of the disease, so that the patients
died without pain, or at least without appearing
to suffer any. In some instances, on
being asked how they were, the patients replied,
“very well,” and called for meat and
drink; but soon after they sunk into a deliquium
animi, in which they remained motionless,
and died.—The pulse was irregular
from the beginning. When there was violent
head-ache, with high delirium, &c. the
pulse was full, hard, strong, and quick; on
the other hand, when these symptoms ceased,
whether shortly after the attack or after the
second or third day, the pulse then became
soft, feeble, intermitting, and not to be
felt[55]. In many instances the skin was dry
and hot, and the patients complained of a
burning sensation, both outwardly and inwardly;
in others the heat was not so great;
in some the skin was yellow; in others it had
a pale corpse-like appearance, joined with
great flabbiness. The diarrhœa was often
accompanied with an incontinence of urine,
both which it was sometimes impossible to
check; in such cases, these symptoms (occurring
together) were the fore-runners of
death. The diarrhœa was common to both
sexes; but the incontinence of urine was observed
in female patients only.
3. The third degree or variety of the plague occurred in the decline of the epidemic. Its
symptoms are the same as those which take
place in the first type; and, therefore, to
avoid repetition, we refer to that[56].
The questions proposed by Prince Orlow to the physicians, and surgeons, were
1. In what manner is the contagion,
which is making such great ravages in this
place, propagated?
2. What are the symptoms which show
that a person is infected with this disorder?
In what respects does it differ from other malignant
fevers, and what symptoms has it in
common with them? How is the patient himself to know that he is attacked with this
dreadful disorder, so as to be able to apply for
help at the very beginning? How are those
who are constantly with the sick, to know
the disorder, so as to be put upon their guard
against taking infection? And, lastly, how
is the physician to be certain that it is the
disease in question[57], in order that all possible
means may be immediately employed to save
the life of the patient?
3. Each of you is required to describe
accurately the symptoms of this disorder
through its whole course and under all its
forms, noticing in what order the symptoms
succeed each other, more especially what the
symptoms are which accompany each crisis,
and what those are which denote more or less
danger: lastly, in what space of time, in
what manner, and with what outward marks
this contagious disorder terminates, whether
it be in recovery or in death?
4. What are the medicines which have hitherto
been administered in the different cases,
in what doses, in what stage of the disorder,
and with what success? The general result
of these observations will determine which
is the easiest and most successful method of
cure.
5. What is it necessary for the patient to
observe when he is taking the remedies, and
when he is not; and what sort of regimen is
best suited to promote the cure?
6. Lastly, each of you is required to make
known, according to his own judgment and
experience, what appear to be the best and
surest methods by which individuals may escape
this terrible scourge, and by which it
may be checked, and if possible entirely eradicated;
but these methods must be simple
and easily put in practice.
My answers to these questions were as
follow:
1. That this contagious disorder was propagated
by touching the sick or dead bodies;
by handling infected goods, such as clothes,
furniture, and the like; by the patient’s
breath; or by the air of a room, confined
and loaded with effluvia from the bodies of
the sick; but not at all by the common atmosphere[58].
Hence those who avoid all
communication with the sick, and never
meddle with infected things, remain free
from the plague, although they live in the
same territory or in the same town where it
is making its ravages; whilst the poor, not
shunning communication with the sick, and
putting on infected clothes, which they buy
cheap or get by inheritance, are continually
exposed to the contagion, and are consequently
those who are chiefly attacked by the plague[59]. Now, if the cause of the
plague existed in the atmosphere, or that it
was carried by it in a state of activity from
one place to another, it should follow, that
all the inhabitants of the same territory, or
at least of the same town, rich as well as
poor, should be equally attacked by it; but this is not the case. All, therefore, that can
be attributed to the atmosphere, with regard
to the plague, is, that according to its different
temperature, it disposes the human body
more or less to receive the contagion; and
that according as its temperature is greater or
less, it renders the pestilential miasm more
or less violent, or even destroys it; which,
indeed, seems to have been the opinion of
other writers on this subject[60]. We have seen
in the preceding narrative, that the cold of
winter blunted, and as it were froze the pestilential
virus, whilst the heat of summer
rendered it more active and volatile; nevertheless,
at both these seasons, the atmosphere
was as healthy as usual.
2. That it was sometimes difficult to ascertain
the existence of the plague on its first
appearance; but that afterwards it was attended
by certain marks, which distinguish
it from every other disease. These characteristic
marks are petechiæ, buboes, and carbuncles.
When these occur in a disorder
which is very rapid in its progress, is accompanied
with fever (unless when it destroys
suddenly) and is highly contagious, there can
be no doubt that such a disorder is the
plague[61].
To determine with certainty whether a disorder
which prevails in any place is the
plague, it must have all the symptoms which
I have just described in one or more patients.
These symptoms taken singly, do not constitute
the plague; for many other disorders
are equally rapid in their course; petechiæ
appear in common putrid fevers; in
some malignant fevers carbuncles are met with; buboes are produced by the venereal
disease and scurvy; and some times, though
very rarely, a crisis happens in putrid fevers
by abscesses forming under the arm-pits; but
these abscesses arise later in these cases than
they do in the plague, and moreover they are
not accompanied with buboes and the other
symptoms which characterize the plague.
The high degree of contagion by which the
disorder is propagated from one person to
another, enters necessarily into the definition
of the plague; without it there is no plague.
In a word, if there is a frequent communication,
either by commerce or in consequence
of war, with Turkey or Egypt, and some
persons, or a great number of persons, are
attacked with a disorder which corresponds
exactly to the definition above given, it is
certain that it is the plague.
3. For the answer to this third question,
the reader has only to revert to the description
of symptoms in note A of the Addenda.
As for the prognosis, it is attended
with great uncertainty in cases of the plague. In some instances, an indisposition apparently
slight, is quickly followed by death; whilst
others who seem to be on the point of death,
recover[62]. In general, when the buboes
suppurate well, and there is a separation of
the eschars from the carbuncles, accompanied
with an abatement of the other symptoms,
a favourable prognostic may be given.
4. That hitherto medicine had done very
little good, the disorder being so rapid in
its course as not to allow time for the remedies
to act; but that the Peruvian bark and
mineral acids, in large doses, ought, in my
opinion, to form the basis of the curative
treatment.
From the preceding history of the plague
it appears, that those who are attacked with
this disorder are affected with nervous symptoms
before the fever comes on, and that the
fever itself is of a highly putrid nature, accompanied
with marks peculiar to itself, and
which distinguish it from all other fevers.
The proportion of those in whom the plague
appears under the form of an inflammatory
fever, is very small: and this happens only
in the beginning of the disorder, in plethoric
subjects; and that in these instances,
from being inflammatory it quickly becomes
putrid. Thus there are two sets of symptoms
in the plague, viz. those which depend
on nervous irritation, and those which depend
on the putrid condition of the blood.
The first I call the nervous, and the second
the putrid state.
In the first, or nervous state, the indication
is to promote perspiration by warm acidulated
drinks, such as infusions of tea and
other herbs mixed with lemon juice or vinegar,
camphorated emulsions, camphor julep
with vinegar and musk, &c. If ever bleeding
is proper, it is at this period, and in plethoric
subjects.
In the second, or putrid state, vomits,
the Peruvian-bark, and mineral acids are the
most promising remedies. The violence and
rapidity with which the disease runs its course,
require that these medicines should be administered
in powerful doses. In the month of
September, a woman, aged twenty-four, was
seized with head-ache, fever, and vomiting;
shortly after, a bubo came out on the right
groin, and another under the arm-pit on the
same side, of the size of a hazel nut; the
next day small petechiæ appeared over the
whole body; she was weak and drowsy; the
tongue was white and moist; the urine pale;
and she complained of head-ache and oppression
about the præcordia. After I had made
her vomit by giving her twenty grains of
ipecacuanha, I ordered her a very strong decoction
of Peruvian bark, to a quart of which
were added a drachm and a half of the extract
of the same bark, a drachm of the acid
elixir of vitriol of the London Pharmacopœia,
and an ounce of syrup of marshmallow;
she took three ounces of this mixture every
other hour, and besides this, she also took four times in the day, half a drachm of
Peruvian bark in powder. For her common
drink, she had a decoction of barley, acidulated
with spirit of vitriol. The buboes
increased gradually, insomuch that in the
space of a few days they were as large as
walnuts; they continued in this state, without
any signs of suppuration. The patient
began to mend regularly, and at the end of
a week, she was almost entirely recovered;
she was then removed, in spite of all my remonstrances
to the contrary, to the hospital,
from which she was dismissed a short time
afterwards, and came to see me, in perfect
health.
By this mode of treatment I am persuaded
that those who have the plague in its moderate
and slow form, may be rescued from death.
This is further confirmed by the cases of three
children, one of whom was only a year old,
and the two others still younger; each of
them had a pestilential bubo in the groin,
accompanied with fever and great debility.
After they had taken the decoction of Peruvian
bark, mixed with the extract, they got
better; the buboes ripened and yielded a
good pus. Two of these children got quite
well; the third was carried off during his
convalescence, by convulsions occasioned by
the teeth. Although this happened in the
month of December, when the disorder, being
more mild, allowed many to recover;
nevertheless these facts serve to establish the
efficacy of the remedy, since the symptoms
of the plague are always worse in children
than adults, and its good effects were seen
in all the three patients at the same time.
But the cure of the plague by the mineral
acids and Peruvian bark, is only to be expected
when the disease appears under its less
violent forms. In a great number of instances
(where the disease has been more violent)
these remedies have been prescribed, not
only without effecting a cure, but even without
retarding death for a moment. Various
other medicines, such as theriaca (which has
been so improperly cried up in the plague)
camphor, dulcified spirit of nitre, &c. have in like manner failed; so that we are compelled
to acknowledge, that the plague (under its
more violent forms) is of such a malignant
nature as not to yield to any medicines with
which we are yet acquainted, howsoever well
adapted they may, à priori, seem to be for
getting the better of this disorder. From
analogy and the preceding facts, I am inclined
to place more reliance upon the Peruvian
bark and acids, given in large doses, than upon
any other remedy; joining with them, to
obviate debility, camphor, elixir of vitriol,
wine, and blisters. Some were relieved by
gentle emetics, such as ipecacuanha. A
surgeon who had brought with him from
England a great quantity of James’s Powder,
prescribed it to several patients; but I never
heard that it answered better than ipecacuanha
or other emetics[63]. Purgatives, even of the most gentle sort, were hurtful; they brought
on a diarrhœa which it was scarcely possible
to check, and which weakened the patients
exceedingly. I consider bleeding to be very
improper in the plague; nevertheless I
would not forbid it entirely, where the disease,
in plethoric subjects, assumes an inflammatory
form, and is accompanied with phrenitis;
which, however, was seldom the case
in the plague at Moscow[64].
5. That during the convalescence, wine,
malt-liquor, kuas (the small beer of Russia) light vegetable food[65], and above all fresh
air, were proper and necessary. The same
diet which is suited to putrid fevers is equally
suited to the plague. Nothing answers better
for raising the drooping spirits and recruiting
the strength of the weak and convalescent,
than well fermented malt liquor, or
wine and water.
6. That as to checking its progress and
entirely eradicating the pestilence, that, in
the present extended state of the disorder,
would be attended with much difficulty; but
that whatever tended to lessen the communication
between the sick and healthy, and
to prevent the latter from coming in contact
with infected clothes, furniture, &c.
would contribute to this end; and that I
hoped the frost would not only weaken the
contagion, but in a great measure destroy it.
When physicians of science and probity
declare that they are convinced of the existence
of the plague in any place, it is incumbent
on the magistrates, without paying
any regard to the contrary opinions of other
practitioners, to take the necessary precautions
for preserving the health of the public,
by removing, as soon as possible, all infected
persons, as well as those who are under suspicion
of being infected, out of the town,
to a house standing by itself, and to surround
the building with guards, in order to cut off
all communication. As it is of great importance
in the beginning of the plague to
suppress it in secret, an infected family may
be removed in the night-time, without giving
rise to any suspicions concerning the disorder;
which if it has, as yet, appeared only
in this family, may be thus extinguished,
without exciting a general alarm[66]. But when several families have become infected,
it is then no longer possible to keep it a secret
from the public, since the precautions which
it is necessary to employ must make it
known. In such a case, the impested, as
well as all those who have dwelt under the
same roofs with them, must be cut off from
all further communication with the rest of
the inhabitants. The clothes and furniture
belonging to the sick (excepting such things
as are of a hard and solid texture, which it
will be sufficient to wash with vinegar) must
be burnt. The goods that are thrown into
the fire must not be touched with the hands,
but be taken hold of by tongs and poles furnished
with hooks at the end[67]; in the same
way, the dead bodies are to be put into the
carts, that carry them to the burying-grounds.
Persons who may be relied on,
should be appointed to see that all these directions
are strictly complied with. The
relations and friends of the sick should be
persuaded to burn the clothes and other effects
which they may at different times have
received; and the health of such friends and
relatives should be well watched by the physicians.
A Board of Health, composed of some
persons of rank, two or three physicians,
and as many of the principal citizens, should
regulate, under the authority of the magistrates,
all matters relative to the health and safety of the inhabitants. This Board or
Committee should divide the town into quarters
or districts, in each of which they should
appoint a physician to visit the sick; they
should enjoin the inhabitants to apprize them
whenever any individual in a family is taken
ill; and they should order that no person be
buried until the corpse shall have been examined
by one of the faculty, and a note be
given certifying the disorder of which the
person died. If there should not be a sufficient
number of physicians, the surgeons
may be employed in this business.
The poverty of the common people, and
the avarice of others in better circumstances,
have, in all places and at all times, been the
chief causes by which the contagion has been
propagated. The poor man, who dreads
hunger more than death, cannot bear to see
himself deprived of the pittance of property
left him by a relation or friend, and accordingly
endeavours to secure in secret all that
he can; whilst the avaricious man, delighted with the thoughts of making a good bargain,
buys what is offered for sale, regardless of
the risk he runs of taking the contagion.
There is but one effectual remedy for this
evil, which, as long as it subsists, renders
all precautions whatever of no avail. The
remedy I mean is to allow a sum of money
from the public treasury for the payment of
the value of the goods which are burnt. In
fact, the condition of those whose family is
attacked with the plague is woful enough;
deprived of their friends and cut off from all
society, they have little else to expect but
death: is it fit, then, that their situation should
be rendered still more deplorable by having
their goods taken from them and destroyed,
without any compensation; and thus to have
no other prospect left them but that of
extreme indigence, in case of recovery? Let
persons be appointed to appraise fairly the
goods which are burnt, and pay for them accordingly;
or, let the money be deposited in
the hands of some banker, or of a committee
chosen for that purpose, with the claimant’s
name, in order that if he recovers, it may be given to him, or in case of death,
to his heirs. Not only those among the poor
who are ill of the plague, but those also who
are suspected of having the contagion, should
be fed and maintained at the public expence;
humanity, as well as the safety of the rest
of the inhabitants, requires that this should
be done. A sufficiently large sum should be
appropriated to this purpose, in order that,
in case of urgency, there may be no difficulties
on this head. If every thing is arranged
in this manner from the first appearance
of the plague, the expences will not be
very heavy, the contagion will be easily stopped,
and the evil will be stifled in its infancy.
When the disorder has ceased, all who have
recovered from it, as well as those who have
attended upon the sick, should remain shut
up for some time until all doubts are removed
as to their being capable of communicating
the contagion, on mixing with the inhabitants
again. Forty days (whence the term quarantine) are the usual probation; but although
this space of time may be requisite
for the complete purification of goods, it seems to be much longer than is necessary in
the case of infected persons, or persons merely
suspected of having the contagion[68]. Before
those who have been performing quarantine
are allowed to have communication with the
rest of the inhabitants, they should be washed
all over with vinegar, should put on new
clothes (their old ones having been previously
burnt, as well as their furniture, &c.) and
have their houses well fumigated. Besides
all this, it will further be proper to make a
strict search for several months after, in
order to be satisfied that the contagion is not
concealed in any part of the town, and that
nobody has locked up infected clothes or
goods in chests, trunks, &c. or hidden them
in any other places; for the plague might,
when least apprehended, spring up again
from such a source. The pestilential germ
confined in clothes or bales of merchandise
acquires a greater degree of virulence, and
may in that manner be transported to very
great distances, and be preserved for a great length of time. The deadly power of this
poison is so much increased by being shut up
in bales of goods closely packed and well
defended from the air, that there are instances
of persons who were seized with the
most violent symptoms and suddenly killed,
on opening them[69]. In the last century, a
twelvemonth after the plague had ceased at
Warsaw, Erndtel, who relates the following
anecdote, passed through that town in order
to attend the Court to Marienburgh and
Dantzic: in the town of Langenfurt, a
coachman’s wife, being near the time of
her lying-in, brought with her in the month
of October a mattress on which some persons,
who had died of the plague a year before,
had lain. Having made use of it, she was
soon seized with the same disorder, accompanied
with inguinal buboes, and was shortly
afterwards delivered; but an hæmorrhage
from the womb coming on, she died, as well
as the child. The husband, also, died soon after, having buboes and carbuncles; and
many other persons caught the infection,
which proved fatal to more than twenty of
them. This contagion continued to manifest
itself until the month of February, without,
however, occasioning any more deaths,
the persons belonging to the Court being
dispersed in different villages and country
seats. It ceased altogether in the beginning
of March[70]. After the plague has spread itself
and become prevalent, its progress is
resisted with much more difficulty, and it
threatens to become a general calamity. We
must not, however, wholly despair; for if,
on the one hand, the Magistrates and the
Committee of Health exert themselves to the
utmost, and on the other, the inhabitants
are tractable, the evil may yet be suppressed,
especially if the season be favourable. The
first object of attention is, to prevent it from
being carried into the neighbourhood and
other places. To this end, it will be proper
to make known in a printed declaration, that the disorder which rages is the plague; that
the contagion does not exist in the air, and
is only communicated by contact of the sick
and infected goods: In this advertisement
the inhabitants should be called upon to obey
punctually the orders which may be given for
the safety of the public at large, as well as
of individuals; they should be warned against
buying clothes or other effects which have
been used; and dealers in second-hand goods
and clothes should not be suffered to carry on
their trade: Further, if the plague rages in
one quarter of the town only, all communication
between that part and the rest of
the town should be immediately cut off.
In the beginning, when only a few families
have become infected, the public safety requires
that they should be sent out of the
town, or at least removed to some detached
building, so as to be deprived of all further
intercourse with the rest of the inhabitants;
but this should be done in a humane and
soothing manner, and with as little inconvenience
as possible to these unfortunate persons. When the calamity, however, has arrived at
such a pitch, that great numbers are attacked
with the disorder, and that it has spread itself
over every part of the town; we can no
longer hope to eradicate it entirely by these
precautions. At this period it would be
cruel and unfeeling to add to the sufferings
of so many afflicted families, by forcing away
the sick from the healthy, by depriving the
father of the presence of his children, the
wife of the attentions of her husband, and
the old man of the comfort of his family.
Under such circumstances, we should only
aggravate the evil, by compelling the sick to
conceal their illness. Besides, it is impossible
to find buildings sufficiently large and
convenient for such a vast number of patients.
Nevertheless, every exertion must
be made to stop the progress of this terrible
disorder, which propagates itself by contagion,
in every direction.
In this melancholy situation what adds to
the distress is, that it is difficult to contrive
measures which shall on the one hand be consistent
with the humanity with which the
unfortunate sufferers should be treated, and
on the other, with the public safety. If you
drag from their houses the fathers of families,
mothers, and children, and thrust them
into hospitals, you rob them of the only
consolation which is left them, you heap
misery upon misery, and plunge them into
despair, from which it is impossible for them
to recover. On the other hand, although
the contrary plan may seem more humane, it
is nevertheless equally cruel and fatal to the
public at large to neglect all precautions, and
to let the contagion take its own course; for
in that case many towns and whole provinces
would become a prey to the pestilence. We
must, therefore, take the mid-way between
these two extremes.
Let an hospital with the houses near it, or
a whole suburb[71], be appropriated for the reception of the poor who are seized with
the plague; let every thing which is requisite
for their support and cure be provided
there; and let them repair thither of their
own accord, and not be brought by compulsion.
Let other persons be allowed to
remain with them, provided the infected
houses have a common mark upon the doors, by which they may be distinguished from the
rest, in order that sound persons who enter
them may be put upon their guard. Let the
Board of Health circulate printed directions
how the uninfected are to manage when they
approach the sick, warning them to keep the
doors and windows open, to avoid the breath
of the infected, and the effluvia from
their bodies and excrements; to sprinkle the
rooms frequently with vinegar; and to avoid,
as much as possible, touching with their bare
hands either the bodies of the sick or infected
goods; or if they have touched them, to
wash their hands immediately with vinegar.
Physicians, surgeons, and nurses, must be
appointed to take care of the impested, and
have handsome salaries allowed them[72].
The Magistrates should take care that the
dead bodies do not remain unburied longer
than is absolutely necessary for determining
the disease by which life was destroyed.
Those who are employed in burying the
dead should be protected from the contagion,
by having cloaks and gloves of oil-cloth,
which should be frequently washed with vinegar;
and that they may not touch the dead
bodies with their hands, they should be provided
with hooks and other instruments for
lifting them up.
The burying-grounds should be out of the
town, and at some distance from the high-roads;
the corpses should be thrown into
deep trenches, and be immediately covered
over with a thick layer of earth, not only to
prevent the effluvia that would otherwise
arise from them, but also to secure them from
dogs and crows.
Although, as I have before remarked, the
atmosphere at Moscow, even when the plague was at its height, was not at all vitiated,
and by no means contagious, not only
in the winter but also in the middle of summer,
when the heat is as great as in any other
parts of Europe, excepting such as lie immediately
to the south; yet, if a great number
of bodies dead of the plague are suffered
to lie unburied and putrefy, they may impregnate
the air with their effluvia to such a
degree as to render the atmosphere (otherwise
incapable of propagating the contagion)
infectious, especially in summer, and thereby
cause it to spread inevitable destruction to the
neighbourhood. It is well known that the
carcases of all animals in a state of corruption
fill the surrounding atmosphere with effluvia
that are accompanied with an intolerable
stench, and that these effluvia, though they
do not produce the plague, are nevertheless
the cause of putrid, malignant fevers. Accounts
are given by several authors of such-like
epidemic diseases being produced by the
fætor exhaled from the dead bodies left on the
field of battle, or from the bodies of animals
putrefying in stagnant waters or on the banks of rivers. Among others, Forestus, (Lib. 4.
Obs. ix. Tom. 1.) gives the history of a very
malignant epidemic, occasioned by an enormous
fish of the whale kind, which lay corrupting
on the sea-shore. But how much
more pernicious effects must the putrefaction
of bodies dead of the plague have, since in
this disorder the simple effluvia from the sick
are so fatal to persons in health?
(The observations which follow on the
airing of goods, on quarantine, &c. coincide
so much with those that are to be found in
every treatise on the plague, that they are
omitted by the Translator.)
The houses and rooms of persons infected
with the plague are purified by firing gunpowder
in them. At Moscow we employed with success a powder, called antipestilential,
of which sulphur and nitre formed the basis;
some bran and other vegetable substances,
such as abrotanum, juniper-berries, &c. together
with certain resins, were added; but
in my opinion these resins are totally useless,
and only increase the expence[73]. The acid vapours let loose on burning nitre and sulphur
together, remain a long time suspended in the
air[74]. The greater or less strength of these
powders depends on the proportion of sulphur
and nitre to the other ingredients. After
burning the rags or other litter which may
be found in the rooms, they are fumigated by
throwing one of these powders on a chafing-dish
or pan of coals, the doors and windows
being shut, to keep in the smoke and vapour
for a sufficient length of time. This vapour
is hurtful to the lungs, and produces suffocation;
hence the person who throws the powder
upon the burning coals should get out of
the room as fast as possible. This process is repeated three or four times in the space of
twenty-four hours for several days together;
after which the doors and windows are
thrown open.
We shall content ourselves with abridging,
rather than translating at full length, what
the author offers on this head. Among other
preservatives, issues are taken notice of. The
author himself had one made in his left arm,
which he kept open for a twelvemonth; but
he is inclined to attribute his exemption from
infection rather to his having avoided the
contact of the sick and infected goods, than
to this remedy. It appears that four surgeons
at the principal pest-hospital died of the
plague, notwithstanding they had all of them
issues. Hence their preservative virtues may
be questioned; yet as they have been recommended
by others, and are attended with
little inconvenience, he thinks it would be proper for those who are obliged to go among
the infected, to have one made in the arm or
leg, or both.—Sweet spirit of nitre was esteemed
an excellent preservative by some;
they took twenty or thirty drops of it upon
a lump of sugar several times a day. Others
took, with the same intention, the Peruvian
bark under different forms; but as they all
kept out of the way of the contagion at the
same time, the preservative powers of these
remedies remain very doubtful. The common
practice of carrying camphor in the
pocket or sewed in the lining of the clothes,
has nothing to recommend it. In like manner
the smoking of tobacco, though it has
been so strongly recommended by Diemerbroeck and others, is by no means a certain
protection against the contagion. The Turks,
says Dr. Mertens, are continually smoking
their pipes; and yet great numbers of them
are swept off by the plague every year. This
reflection was not sufficient to do away the
prejudice in its favour, so difficult is it to destroy
a received opinion, howsoever false it may
be. While the plague was raging at Moscow,
many Russian gentlemen and foreigners had recourse to the smoking of tobacco, as an infallible
preservative. Those who were accustomed
to the pipe, smoked oftener, whilst
others gradually brought themselves to bear
it, until they saw some among the foreigners
of the lower class carried off by the plague,
in spite of the use of this remedy. The
master chimney-sweeper at the foundling-hospital,
who had formerly served in the
Prussian army, had so much faith in the
smoking of tobacco, that he was always seen
with a pipe in his mouth from morning to
night; and boasted that by this means he
should be proof against the plague. Disregarding
all other precautions, even when the
disorder was at its height, (viz. the month of
September) he got over the fences in the
night-time, in order to go and see his wife
and children who were in the town. He was
immediately seized with head-ach and vomiting,
and the next day he had a bubo in the
groin and under the arm-pit, accompanied
with great debility and fever. He died at
the end of forty-eight hours. His apprentice,
twelve years of age, had a large flat bubo under
the armpit, and followed him soon after.
From the account published by Count Berchtold at Vienna, in 1797, it would appear
that the best preservative method is that recommended
by Mr. Baldwin, the British Consul
at Alexandria. It consists simply in anointing
the body all over with olive oil. According
to the same account, friction with
warm oil is not only a preservative, but also a
curative remedy. See the second volume of Duncan’s Annals of Medicine.
I shall now give a particular account of the
means by which the Foundling Hospital was
kept free from the plague, during the whole
time that it raged at Moscow; in the last six
months of which it swept off so many thousands
of inhabitants. From this account it
will easily be seen how possible it is in times
of pestilence, to keep one’s self, one’s family,
and whole buildings, not only private
but public, free from infection.
The Foundling Hospital[75] is situated in
the middle of the city, at the conflux of the
Yausa and the Moscua. It occupies a space
of ground, at that time only inclosed by a
hedge six feet high, whose circumference
measures nearly a French league. On this
has been erected a building which might easily
be made to contain five thousand foundlings.
That part of it which was finished in 1769,
contained one thousand children and three
hundred adults; the rest, consisting of masters,
servants, workmen, and soldiers, who
amounted to nearly one hundred, lived in
houses built of wood adjoining the stone edifice
and standing within the inclosure. This
inclosure had three gates.
In the month of July, as soon as I found
that the plague had spread itself in the town,
I requested the Governors of the hospital to
order all the gates to be shut, excepting that
where the porter lived; and not to suffer any
person to come in or go out, without permission
from the principal inspector. I further
requested them to lay in a large stock, from
places not yet infected, of flour, cloth, linen,
shoes, and other necessaries. In the month
of August, when the plague was raging with
great fury, it was no longer permitted for any
one to enter but myself. Persons who lived
out of the enclosure were hired to purchase
all the necessaries of life, and to carry letters.
I gave the porter some written directions, in
which I put down every thing he was to allow
to enter, and under what precautions.
The butcher threw the meat into large tubs
filled with vinegar, from which it was afterwards
taken out by the under-cook. I prohibited
the admission of furs, wool, feathers,
cotton, hemp, paper, linen, and silk; but I
allowed sugar-loaves to be received, after taking
off the paper and packthread. Letters were pricked through with a pin and afterwards
dipped in vinegar, and dried in the
smoke produced by burning juniper-wood.
The inhabitants of the building were allowed
to speak to their relations and friends, who
stood at a certain distance out of the gate[76].
Being obliged to purchase two hundred pair of
boots and shoes, in the month of October;
I ordered them to be immersed for some
hours in vinegar, and afterwards dried.
I visited all the sick in the house twice
every day; the sound were examined by two
surgeons night and morning, who informed
me whenever they found any of them indisposed.
Whenever any symptoms occurred
in a patient which appeared to me doubtful,
I kept such patient apart from the rest, until
I was satisfied the disorder was not the
plague. In this manner I detected the plague seven times among the soldiers[77] and workmen
belonging to the Foundling Hospital;
but as I separated them on the first appearance
of the symptoms, they none of them
infected the others, except the master chimney-sweeper,
who gave it to his apprentice.
After the month of July, we ceased to admit
any more foundlings or pregnant women. I
proposed to the Governors to hire, in the
mean while, a house for this purpose in the
suburbs, which was not determined upon
until the month of October[78]. At this time
there still continued to die in the town above a thousand persons in a day. I had the children
who were brought to this quarantine-house,
stripped to the skin; after which their
clothes were burnt, their bodies washed all
over with vinegar and water, and new clothes
put upon them. I kept them for the space
of a fortnight in three rooms detached from
the rest; if, after that time, no signs of the
plague appeared among them, they were put
(having previously changed their clothes) each
in the order in which he finished this first
term of probation, in the common dwelling-rooms
of the quarantine-house; here they
remained another fortnight, before they were
removed to the Great Hospital. I visited
every day these children and the lying-in women[79].
One infant was brought with a pestilential
bubo, and two others, during the time
of their quarantine, had the plague with buboes,
as mentioned in a former part of this treatise. By putting them in separate rooms
along with their nurses, the contagion was
prevented from spreading[80]. I had thus the
happiness of rescuing from death about one
hundred and fifty children[81], brought to the
quarantine-house after the month of October.
In the Spring of 1772, every thing was
restored to its former footing.
THE END.